Abstract Diffuse large B-cell lymphoma (DLBCL) exhibits significant genetic heterogeneity which contributes to drug resistance, necessitating development of novel therapeutic approaches.Pharmacological inhibitors of cyclin-dependent kinases (CDK) demonstrated pre-clinical activity in DLBCL, however many stalled in clinical development.Here we show
Experiencing and processing emotions, especially profound grief following a significant loss, provides deep personal insights and understanding that can inform the study of emotional practices and customs related to death and mourning.This paper explores how emotions, from basic to complex, are studied through historical artefacts, evolutionary bio
ABSTRACT Objectives: to evaluate the effectiveness of carbohydrate popsicles, carbohydrate solution, and usual care (fasting) on the intensity and discomfort of preoperative thirst.Methods: a randomized clinical trial with 60 preoperative patients aged between 18 and 60 years, randomized into three groups: control (fasting), carbohydrate solution (
Berm breakwaters are used as protective structures against the wave attack where Grill Dish Support Shelf larger quarry materials as armor stone is scarce, or large quarry materials are available but using berm breakwater lowers the costs considerably.In addition, wave overtopping in berm breakwaters are significantly lower than the traditional one